BRCA2 anticorps (C-Term)

N° du produit ABIN7450040

L’anticorps Lapin Polyclonal anti-BRCA2 a été validé pour WB et IP. Il convient pour détecter BRCA2 dans des échantillons de Humain.

Aperçu rapide pour BRCA2 anticorps (C-Term) (ABIN7450040)

Antigène: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRCA2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-BRCA2 anticorps

Épitope: C-Term

Fonction: Rabbit anti-BRCA2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 3350 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BRCA2

Antigène: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Autre désignation: BRCA2

Sujet: Background: BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar, however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1.

ID gène: 675

NCBI Accession: NP_000050

UniProt: P51587

Pathways: Réparation de l'ADN, M Phase, Maintenance of Protein Location